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Year : 2014  |  Volume : 19  |  Issue : 1  |  Page : 80-81

Multiple choice questions on Rheumatology

Date of Web Publication1-Feb-2014

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How to cite this article:
. Multiple choice questions on Rheumatology. J Mahatma Gandhi Inst Med Sci 2014;19:80-1

How to cite this URL:
. Multiple choice questions on Rheumatology. J Mahatma Gandhi Inst Med Sci [serial online] 2014 [cited 2021 Dec 6];19:80-1. Available from: https://www.jmgims.co.in/text.asp?2014/19/1/80/126271

1. Which of the following is not a criterion for remission in rheumatoid arthritis (RA) according to the ACR/EULAR 2011 criteria?

  1. C-reactive protein (CRP) #8804;1 mg/dL
  2. Swollen joint count ≤1
  3. Tender joint count ≤1
  4. Physician global assessment ≤1

2. A 45-year-old female complaints of increasing widespread joint pains which are worse in the evening after a stressful day at work. She describes puffy hands and feet and a painful neck. Her concentration is very poor and she has recently suffered from marital problems. Rheumatoid factor is mildly positive. Examination reveals an increased body mass index and global restriction of movement due to pain, but no synovitis. Which of the following investigations would be useful in this case?

  1. Anti-cyclic citrullinated peptide antibody
  2. Ultrasound scan hands and feet
  3. Anti-JO-I antibody
  4. Erythrocyte sedimentation rate and C reactive protein
  5. Anti-mitochondrial antibody

3. Which of the following drugs is most likely to cause systemic lupus-like syndrome?

  1. Baclofen
  2. Isoniazid
  3. Methotrexate
  4. Procainamide
  5. Sulfasalazine

4. A 25-year-old female gives birth to a baby with complete heart block who subsequently requires pacemaker insertion. Which of the following antibodies is most likely to be detected in the maternal serum?

  1. Anti-double-stranded deoxyribonucleic acid (dsDNA) antibodies
  2. Anti-endomysial antibodies
  3. Anti-Ro/SSA antibodies
  4. Anti-SCL70 antibodies
  5. Rheumatoid factor

5. Which of the following is a pro-inflammatory cytokine?

  1. CRP
  2. Interleukin 4 (IL-4)
  3. IL-10
  4. Serum amyloid precursor protein
  5. Tumour necrosis factor-alpha

6. A 72-year-old man presents with an acutely painful right knee. On examination, he had a temperature of 37΀C with a hot, swollen right knee. Of relevance amongst his investigations, was his white cell count which was 12.6 Χ 10 9 /l and a knee X-ray revealed reduced joint space and calcification of the articular cartilage. Culture of aspirated fluid revealed no growth. What is the most likely diagnosis?

  1. Gout
  2. Psoriatic monoarthropathy
  3. Pseudogout
  4. Rheumatoid arthiritis
  5. Septic arthritis

7. Which of the following regarding Infliximab is most true?

  1. Is a monoclonal antibody to the glycoprotein IIb-IIIa receptor
  2. Is authorized for the treatment of severe ulcerative colitis
  3. Is licensed for the treatment of RA
  4. It prevents relapse of Crohn's disease in patients who are in remission
  5. Must not be used in combination with methotrexate due to increased toxicity

8. A 25-year-old lady with known systemic lupus erythematosus (SLE) presents with the nephrotic syndrome. A renal biopsy is performed and this confirms diffuse proliferative glomeronephritis (WHO Class IV). Which of the following treatment regimens would you advise?

  1. Azathioprine alone
  2. Prednisolone alone
  3. Azathioprine and prednisolone
  4. Prednisolone and intravenous cyclophosphamide
  5. Prednisolone and methotrexate

9. Which of the following auto-antibodies may have a role in monitoring disease activity?

  1. Rheumatoid factor in RA
  2. Antinuclear antibodies in SLE
  3. Anti-Sm antibodies in SLE
  4. Anti-dsDNA antibodies in SLE
  5. Anti-Ro (SSA) antibodies in Sjogren's syndrome

10. A 69-year-old woman taking hydralazine for hypertension presents with joint pain and chest pain. On cardiac examination, the patient has a pericardial rub. What is the diagnosis?

  1. Dermatomyositis
  2. SLE
  3. Polymyalgia rheumatic
  4. Felty syndrome

  Answers Top

  1. Physician global assessment <1
  2. a, b and d
  3. Procainamide
  4. Anti-Ro/SSA antibodies
  5. Tumor necrosis factor-alpha
  6. Pseudogout
  7. Is licensed for the treatment of RA
  8. Prednisolone and intravenous cyclophosphamide
  9. Anti-dsDNA antibodies in SLE
  10. SLE


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