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| LETTER TO THE EDITOR |
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| Year : 2018 | Volume
: 23
| Issue : 2 | Page : 104 |
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Retroperitoneal paraganglioma: A case report with review of literature
Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
| Date of Web Publication | 11-Oct-2018 |
Correspondence Address:
Prof. Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, P.O.Box 55302, Baghdad Post Office, Baghdad
Iraq
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jmgims.jmgims_26_18
How to cite this article:
Al-Mendalawi MD. Retroperitoneal paraganglioma: A case report with review of literature. J Mahatma Gandhi Inst Med Sci 2018;23:104 |
Sir,
I read with interest the case report by Hungund et al. on the retroperitoneal paraganglioma (RP) in an Indian patient published in the latest issue of J Mahatma Gandhi Inst Med Sci.[1] The authors nicely described the clinical picture, radiological features, histopathologic findings, and the treatment protocol in the studied patient. I presume that the rare occurrence of paraganglioma at an unusual site ought to trigger the authors to take into consideration underlying jeopardized immune status in the studied patient. Among jeopardized immune states, infection with human immunodeficiency virus (HIV) is of great importance. My presumption is based on the following point. It is explicit that HIV-positive individuals are more susceptible to various types of neoplasms as compared to immunocompetent individuals. The increased susceptibility has been attributed to many factors, including immunosuppression, coinfection with oncogenic viruses, and life prolongation secondary to the use of antiretroviral therapy.[2] Among neoplasms, paraganglioma has been reported among HIV-positive patients.[3] To my knowledge, HIV infection is an important health threat in India. The available data pointed out to 0.26% HIV seroprevalence compared with a global average of 0.2%.[4] I presume that the authors ought to consider underlying HIV infection in the studied patient. Hence, contemplating the diagnostic set of blood CD4 lymphocyte count and viral overload estimations was envisaged. If that diagnostic set was achieved and it revealed HIV infection, the case in question could be truly considered a novel case report. This is because HIV-associated RP has never been reported in the world literature so far.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
| References | |  |
| 1. | Hungund BR, Pattanshetti VM, Pilli GS, Kangle R, Chavan RY. Retroperitoneal paraganglioma: A case report with review of literature. J Mahatma Gandhi Inst Med Sci 2018;23:37-9.  [Full text] |
| 2. | Valencia Ortega ME. Malignancies and infection due to the human immunodeficiency virus. Are these emerging diseases? Rev Clin Esp 2018;218:149-55. |
| 3. | Fasunla AJ, Ibekwe TS, Afolabi OA, Onakoya PA, Oluwasola OA, Ogun OG, et al. Sinonasal paraganglioma: A case report. Oral Maxillofac Surg 2008;12:93-6. |
| 4. | Paranjape RS, Challacombe SJ. HIV/AIDS in India: An overview of the Indian epidemic. Oral Dis 2016;22 Suppl 1:10-4. |
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